Recognizing Early Multiple Sclerosis (MS) Symptoms and Why It’s Important Not to Ignore Them. MS affects the brain and spinal cord, often starting between the ages of 20 and 40. The symptoms can vary, but here are some of the key early signs to watch for: - Vision problems: Blurry vision, eye pain, or trouble seeing colors clearly—often a sign of optic neuritis. - Fatigue: Unexplained exhaustion that doesn’t improve with rest. - Numbness and tingling: Particularly in limbs, this can be a warning