More than 160 million Americans are on alert for a "potentially catastrophic" winter storm, including heavy snow and brutal cold, stretching over 2,000 miles from New Mexico and Texas all the way to Maine. Several states have declared a state of emergency. Whit Johnson reports. https://abcnews.link/fM7XlfU | ABC World News Tonight with David Muir

Amid a massive winter storm, more than 2,000 snow plows are working around the clock in New York City to clear the streets before snow turns to ice overnight. Officials say they are investigating the deaths of 5 people that may be related to the plunging temperatures. Whit Johnson reports. https://abcnews.link/nZuIH2x | ABC World News Tonight with David Muir

CIVILIANS CAUGHT IN THE CROSSFIRE: Russia has intensified attacks as Ukrainian officials say over 2,000 civilians have been killed since the Russian invasion. Ian Pannell reports from Kyiv. https://abcn.ws/3sApo3O | ABC World News Tonight with David Muir

Researchers from a new study say they found that consuming the preservatives used in foods such as deli meat, bacon and cereal is associated with a higher risk of developing cancer. David Muir reports. | ABC World News Tonight with David Muir