In molecular biology, extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that are involved in functions including the …

Extracellular signal-regulated kinase (ERK) has long been studied as a key driver of both essential cellular processes and disease. A persistent question has been how this single pathway is able to …

Dec 24, 2023 · The ERK pathway is a key cell signaling system activated by physiological factors or oncogenic mutations, influencing different cell outcomes. The protein kinases ERK1 and ERK2 …

Jun 23, 2020 · By phosphorylating widely diverse substrates, ERK proteins govern a variety of evolutionarily conserved cellular processes in metazoans, the dysregulation of which contributes to …

Extracellular signal-regulated kinases (ERKs) are widely used intracellular serine/threonine-protein kinase signaling molecule that regulates a variety of cellular functions, including mitosis, meiosis and …

The extracellular-signal-regulated kinase (ERK) pathway is one of the major signaling cassettes of the mitogen activated protein kinase (MAPK) signaling pathway.

Dec 23, 2025 · Explore the ERK pathway and its role in cell proliferation and survival. Click here to read more about this critical signaling pathway.

Read our article on The ERK Signal Transduction Pathway and its role in growth factor signaling and cancer.

Apr 9, 2018 · The ERK (extracellular-signal-regulated kinase) signaling controls several cellular processes such as cell growth, proliferation, differentiation and apoptosis.

The ERK pathway plays an important role of integrating external signals from the presence of mitogens such as epidermal growth factor (EGF) into signaling events promoting cell growth and proliferation …