Research has uncovered a surprising biological twist: molecules that help support healthy aging can also contribute to cancer growth.

KLF5 appears to fuel pancreatic cancer metastasis by reprogramming epigenetic controls, offering a potential new therapeutic target.

Diseases from bacterial pathogens have been a major concern worldwide and are the major cause of mortality and morbidity. Dendritic cells and macrophages ...

Russia has forcefully deported at least 20,000 Ukrainian children since the beginning of its full-scale invasion. Kyiv ...

Pasca Lab specializes in growing three-dimensional organoid models from reprogrammed stem cells, which capture molecular changes during fetal brain-like development. Because the human brain cannot be ...

After treatment, the mice’s memories were essentially shunted back into a younger state. The researchers found that reprogrammed engrams displayed molecular behavior of more youthful cells. Using a ...

Regenerative medicines are headed for people with Parkinson’s disease or severe heart failure — but researchers are concerned about minimal clinical-trial data.

HER2-positive gastric cancer accounts for a substantial proportion of advanced cases and has long been treated with HER2-targeted therapies. While trastuzumab deruxtecan has shown superior activity ...

The Trade-off Between Physiological Authenticity and Experimental Convenience: Navigating the Cellular Foundation of ...

Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have shown for the first time that, before they can start developing into egg and sperm cells, the embryonic ...

In human cells, DNA carries chemical or "epigenetic" marks that decide how genes will be used in different tissues. Yet in a ...

A groundbreaking clinical trial is testing whether specially engineered stem cells can help the brain restore its own ...