Israel said it had struck uranium enrichment sites in Iran after the two countries launched another barrage of missiles at ...

Iran's supreme leader warned the U.S. would face "irreparable damage" if it joined Israel's conflict with Iran. Who is ...

Israel and Iran are waging an existential battle. What does it mean for the US?: ANALYSIS When did Khamenei come to power?

Ayatollah Ali Khamenei rejected President Trump's demand for unconditional surrender, as Iranians jammed the highways out of ...

Calling out Trump directly, the Supreme Leader added: “The U.S. President threatens us. With his absurd rhetoric, he demands ...

The cleric has ruled for more than three decades, spearheading a policy of backing proxy groups to wield influence across the ...

Ayatollah Ali Khamenei has spent almost four decades as Shi'ite Iran's supreme leader building a regional power to rival the ...

In an ABC News exclusive, Israeli PM Benjamin Netanyahu speaks with Jon Karl about the conflict with Iran -- and says he's not ruling out taking out Iran's supreme leader, Ali Khamenei.

"We're doing what we need to do," Israeli PM Benjamin Netanyahu tells Jon Karl about the possibility of taking out Iran's ...

Israel launched strikes on Iran’s capital early Friday, with explosions booming across Tehran as Israel said it targeted ...

Ayatollah Ali Khamenei, Iran's supreme leader for over three decades, now faces open threats from the US and Israel amid ...