For the first time ever, the NFL will play a game on “Thanksgiving Eve” with a standalone showcase on Wednesday, November 25. Green Bay visits the L.A. Rams for an 8 p.m. ET primetime kickoff. That contest and the Black Friday game bookend the usual three Thursday matchups.

The NFL Thanksgiving week slate is stacked. See the odds for the four primetime matchups.

The Chicago Bears once again will play the Detroit Lions on Thanksgiving Day at Ford Field in Detroit. For the second time in three years and the fifth time since 2018, the Bears and Lions will kick off the NFL’s Thanksgiving slate at noon CT on CBS.

The NFL has released its full schedule for the 2025 season. Football fans everywhere will now pore over it, assessing how their favorite teams may do and circling marquee matchups. It will also allow NFL fans and analysts alike to identify which teams have the most and least favorable schedules.