Researchers found a new way to kill harmful “zombie” cells that linger after chemotherapy and help cancers become more ...

A team led by Spaniard David Lagares is searching for a treatment for pulmonary fibrosis and other ailments associated with ...

Understanding how muscle deteriorates could help researchers extend the human health span. “When you ask most older adults what their biggest fear is, it’s not dying — it’s loss of functional ...

Senescent CD8+ T cells impair CAR T therapy by reducing cell growth, migration, and tumor killing, with gene signatures ...

A newly identified weakness in “zombie” cells may open the door to more precise cancer treatments by turning their own ...

You know how one fender-bender can block up traffic for hours, fueling road rage? Well, the same thing happens when your LDL cholesterol level is too high and it bangs up your liver by contributing to ...

Senescent cells walk a tightrope, risking cell death with high levels of iron and other damaging agents, but compensating for this by overproducing a protective protein, GPX4, which staves off death.

People who carry the APOE2 version of the apolipoprotein E gene are more likely to live to advanced age and are partly ...

The APOE2 gene variant protects against Alzheimer's by enhancing DNA repair and preventing neuronal senescence.

Hartono and colleagues report a non-invasive strategy that uses urine to monitor senescence and the effect of therapies that eliminate senescent cells. Given the increasingly acknowledged role of ...

A new set of drugs exploit a recently revealed weakness in "zombie-like"—or senescent—cells that could lead to new treatments for cancer and age-associated diseases. The study from the MRC Laboratory ...