The common analogy of drug action is that of a lock and key, with a drug acting as a selective 'key' that fits into the 'lock' of a specific drug target. Over the past two decades, the concept of ...

Time-resolved cryo-electron microscopy during activation of Gα i1 βγ and Gα 11 βγ heterotrimers bound to NTSR1 enables isolation of multiple transient complexes along the activation pathway and ...

Abstract: Due to the difficulty of achieving hemostasis in deep-seated vessels without compromising tissue perfusion, a novel hemostatic balloon is proposed in this work. The balloon features a hollow ...

You will be redirected to our submission process. The "Rising Stars in Drug Metabolism and Transport 2025/2026" highlights the groundbreaking work of early-career researchers who are making ...