In an interview earlier with US Magazine earlier this summer, Williams detailed the pain and struggle associated with her 30-year battle with uterine fibroids, which was officially diagnosed in 2016.

Carlos Alcaraz opens his bid for a sixth Grand Slam title at the US Open on Monday as Venus Williams prepares to make a record-extending 25th appearance at the tennis

In the men's draw, Alcaraz did not have an easy first round for his debut at Flushing Meadows. Facing the excellent server Opelka, the Spaniard did not falter, winning in three sets (6-4, 7-5, 6-4) and securing his 55th win of the year,

The best matches of day 2 include Williams' return to the singles at 45, Alcaraz's tricky opener and Victoria Mboko's debut as a seed.

Carlos Alcaraz, Coco Gauff and the world's biggest tennis stars are squaring off in New York over the next two weeks