Researchers have used cryo-electron tomography to uncover new details of the molecular structure of synaptic vesicles, which help transport neurotransmitters in the brain. The study could inform ...

"Synaptic vesicles are of paramount importance in brain function and they have been studied for decades. However, previous reports have described the molecular composition of an 'average' synaptic ...

Researchers at Johns Hopkins Medicine say they unexpectedly found new information about a protein's special role in getting brain cells to communicate at the right time and place in experiments with ...

How do we think, feel, remember, or move? It all depends on transmission of chemical signals in the brain, carried and released by molecular containers called vesicles. In a new study, researchers ...

For decades, neuroscientists have debated whether synaptic vesicles “kiss-and-run” or do an irreversible “full collapse” when releasing neurotransmitters. Now, a team in China has frozen that moment ...

Synaptic pathology is increasingly recognised as central to the development and symptomatology of schizophrenia and mood disorders. In schizophrenia, a convergence of genetic risk variants and ...

Bioengineers and neuroscientists at the Wu Tsai Neurosciences Institute at Stanford University have developed a highly sensitive tool for detecting brain cells' subtlest electrical signals. Published ...

For all its mysteries, the brain can sometimes be described through simple metaphors. For example, communication between neurons works in many ways like a busy shipping depot: components come in, ...

Synaptic pruning is a crucial neurodevelopmental process through which the brain refines its neural circuitry by systematically eliminating excess or weak synaptic connections. During early childhood ...

Max Delbrück Center for Molecular Medicine in the Helmholtz Association Researchers led by Uljana Kravčenko and her colleagues in the lab of Professor Misha Kudryashev, Group Leader of the In Situ ...