We have previously shown that HIPK1 is desumoylated in response to TNF leading to its cytoplasmic translocation and involvement in TNF-induced ASK-JNK signaling. 21 However, the mechanism by which TNF ...
Researchers have found a protein that enables cellular survival during periods of low oxygen, or hypoxia, which also is key for development of many kinds of cancer. Researchers believe tumors adapt to ...
HOUSTON - When SUMO grips STAT5, a protein that activates genes, it blocks the healthy embryonic development of immune B cells and T cells unless its nemesis breaks the hold, a research team led by ...
To better understand why some people adapt well to life at high altitude while others don't, researchers studied red blood cells derived from representatives of both groups living in the Andes ...