Two separate laboratory breakthroughs have produced RNA molecules that can build copies of themselves or assemble functional structures without any help from proteins or DNA. These results offer the ...

A 45-nucleotide strand of RNA can now synthesize both its mirror-image complement and a copy of itself, bringing scientists closer than ever to demonstrating how life could have emerged from chemistry ...

Researchers at the MRC Laboratory of Molecular Biology in Cambridge have discovered a ribozyme that is shockingly small, yet ...

A strand of RNA just 45 nucleotides long has been discovered to perform two key reactions required for self-replication. The ...

Cambridge, have discovered a tiny RNA molecule capable of copying itself - a key step toward understanding how life may have ...

Life runs on instructions you never see. Every cell reads DNA, turns that message into RNA, and then builds proteins that ...

Researchers developed C28, an engineered polymerase that efficiently synthesizes RNA at near-natural speeds with high accuracy. Created through directed evolution, the enzyme also performs reverse ...

The relationship between RNA sequences and their resultant structures is central to understanding evolutionary processes and molecular robustness. Genotype–phenotype mapping studies reveal how subtle ...

From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But as their use continues to grow, so does a fundamental challenge: producing RNA ...

Researchers recovered a 250-year-old cold virus from preserved lung tissue, offering rare insight into how respiratory viruses evolved.

Prospects for understanding the origin of the RNA world / Gerald F. Joyce and Leslie E. Orgel -- Reading the palimpsest: contemporary biochemical data and the RNA world / Steven A. Benner ... [et al.] ...