In pharmaceuticals, PXRD is most commonly used to detect traces of polymers. Better detectors and optical technologies are being developed primarily to push the limits of detection (LOD) still lower.
X-ray diffraction patterns of theophylline monohydrate (Theo-FM) held at 5% rH collected between 5 ËšC and 83 ËšC. Conversion from the monohydrate to a metastable form occurs (Theo-Meta). At 55 ËšC the ...