Genotyping single point mutations in rd1 and rd8 mice using melting curve analysis of qPCR fragments
Many diseases such as haemophilia, Duchenne muscular dystrophy, or retinal degeneration are caused by mutations of single nucleotides. Such diseases are rare but the effects are often very destructive ...
The detection of changes in nucleic acid sequences at specific sites remains a critical challenge in epigenetics, diagnostics and therapeutics. To date, such assays often require extensive time, ...
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