Transient cell–cell interactions involving presynaptic neurons and cells that are extrinsic to the neural circuit have important roles in the assembly of the nervous system. In contrast to classically ...

Studying the process of brain formation illuminates just how much of development is a series of tiny miracles. Only a few weeks after a human egg is fertilized, a sheet of cells called the neural ...

The first step in shaping the brain is that the neural plate, a sheet-like cell layer, curves to form the neural tube. Scientists have now shown that during the process of neural tube formation a ...

This is a preview. Log in through your library . Abstract olig genes encode a previously unrecognized group of vertebrate-specific basic helix-loop-helix transcription factors. As shown in mice, ...

Researchers have conducted a detailed study of neurulation -- how the neural tube forms during embryonic development. They conclude that this happens less actively than previously thought. This also ...

Spina bifida is characterized by an opening of the spine, which originates from the formation of the neural tube in the first month of development of the embryo. Three weeks after conception, the ...

Based on conserved developmental principles, we have developed a simple but highly efficient platform to convert human PSCs into neural tissue. We have shown that dual-SMAD inhibition via small ...

Neuroepithelial cells are stem cells that differentiate into neurons and glia, essential components of the human central nervous system, following the process of neurogenesis. Also known as ...

This is a preview. Log in through your library . Abstract The neural crest, a multipotent embryonic cell type, originates at the border between neural and nonneural ectoderm. After neural tube closure ...