A single injection of a gene therapy built around synthetic super-enhancers eliminated aggressive brain tumors in 83 percent ...

Most cancer treatments are based on using the maximum tolerated dose of a drug to kill as many cancer cells as possible. While this approach has led to patients achieving good responses to therapy, ...

Chimeric antigen receptor (CAR) T-cell therapy shows significant potential in treating various human cancers. Unfortunately, researchers have faced difficulty in adapting this therapy to target solid ...

A recent Scientific Reports study used a mathematical model to assess the efficacy of a new combinational therapy of AZD9496 and palbociclib for breast cancer (BC) treatment. Study: A new treatment ...

Cost-related issues have decreased as many drugs have become generic, but adherence still remains a challenge.

Researchers demonstrate how mathematical modeling combined with dynamic biomarkers can be used to characterize metastatic disease and identify appropriate therapeutic approaches to improve patient ...

Cell and gene therapies are exciting new modalities that have the potential to treat, and even cure, a range of diseases that may not be possible with small molecules or monoclonal antibodies. However ...

Nanoparticle-mediated hyperthermia for cancer therapy is a growing area of cancer nanomedicine because of the potential for localized and targeted destruction of cancer cells. Localized hyperthermal ...