CNN — This story contains spoilers from Thursday's episode of "Grey's Anatomy." Dr. Alex Karev has officially done his last shift on "Grey's Anatomy." The sudden departure of actor Justin Chambers ...
ABC's Grey's Anatomy is currently in its 22nd season. Throughout its run, the medical drama has said goodbye to fan-favorite characters like Patrick Dempsey's McDreamy and Sandra Oh's Cristina Yang.
Katherine Heigl, Patrick Dempsey, and Justin Chambers are among the OG stars who've left the series.
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