The DNA-repair mechanism referred to as non-homologous end-joining (NHEJ) involves the Ku proteins (Ku70 and Ku80), DNA ligase IV and Lif1/XRCC4. Meiotic cells down-regulate NHEJ, to favour homologous ...
Three biochemical steps of the non-homologous DNA end-joining (NHEJ) process. This figure outlines the key stages of the NHEJ repair mechanism following DNA double-strand breaks. The process can be ...
Illustration showing how autophagy induction increases the efficiency of precise gene editing. In normal cells, DNA breaks caused by CRISPR–Cas9 are frequently repaired through non-homologous end ...
The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...
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