Since plumbagin treatment showed a minor effect on SP-BER, we focused our studies on LP-BER. The LP-BER activity determined with the F-DNA substrate slightly decreased in extracts from ...
Flap endonuclease-1 (FEN1) is a multifunctional, structure-specific nuclease that has a critical role in maintaining human genome stability. FEN1 mutations have been detected in human cancer specimens ...