Nature

The combination of CSF neurofilament light chain and glial fibrillary acidic protein improves the prediction of long-term confirmed disability worsening in multiple sclerosis

Our objective was to evaluate the individual and combined prognostic attributes of baseline serum and CSF measurements of Neurofilament light chain (sNfL, cNfL) and glial fibrillary acidic protein ...
Nature

A previous champagne tap reduces the probability of traumatic lumbar puncture in the following procedure

A cerebrospinal fluid (CSF) sample containing no red blood cells (RBC), colloquially known as a champagne tap, is an ideal outcome of a lumbar puncture (LP). In this pseudoprospective study of 2573 ...
ALZFORUM

Are CSF Assays Finally Ready for Prime Time?

This story was updated on 18 April 2017 to correct an error. Cerebrospinal fluid biomarkers of Alzheimer’s disease have transformed clinical research, but ...
Labroots

Detection of Human Herpesvirus 6 in Pediatric CSF Samples: Causing Disease or Incidental Distraction?

Director, Molecular Microbiology Assistant Director, Clinical Microbiology and Immunoserology Laboratories Nationwide Children's Hospital Associate Professor - Clinical, College of Medicine, The Ohio ...
ALZFORUM

It’s Official: CSF Aβ42 Reference Standard Will Unify Assays

Studied since the early 1990s, cerebrospinal fluid Aβ42 is the most established fluid marker for detecting early Alzheimer’s disease, yet trying to turn it into a clinically certified, broad-based ...