Mitochondrial ADP/ATP carriers import ADP into the mitochondrial matrix and export ATP to the cytosol to fuel cellular processes. Structures of the inhibited cytoplasmic- and matrix-open states have ...
Scientists at the MRC-MBU in Cambridge, U.K., have discovered how a key transport protein, called the mitochondrial ADP/ATP carrier, transports adenosine triphosphate (ATP), the chemical fuel of the ...
In order to play its central role in protein biogenesis, the endoplasmic reticulum (ER) of nucleated cells depends on an Hsp70-type molecular chaperone, termed immunoglobulin heavy chain binding ...